Sarah Krautwurst, M. Sc.
Main research focus
After focusing on protein bioinformatics during my undergraduate studies, I combined this area with RNA bioinformatics in my master's thesis. Thus, my research is currently focused on RNA-protein interactions (RPIs). RPIs are ubiquitous throughout the kingdom of life and play essential roles between and within organisms. My goal is to develop models and algorithms to understand the mechanisms of these interactions better. To this end, using known RPIs, universal and specific rules are derived based on both sequence and structural information of the interacting partners. Because viral RPIs are generally less well understood, they are of particular interest.
Since the landscape of RPI prediction methods still needs improvement, I hope to contribute to developing an RPI prediction tool that will enable the reliable detection of promising novel RPIs in various organisms.
- "The International Virus Bioinformatics Meeting 2022."
F. Hufsky, D. Beslic, D. Boeckaerts, S. Duchene, E. González-Tortuero, A.J. Gruber, J. Guo, D. Jansen, J. Juma, K. Kongkitimanon, A. Luque, M. Ritsch, G. Lencioni Lovate, L. Nishimura, C. Pas, E. Domingo, E. Hodcroft, P. Lemey, M.B. Sullivan, F. Weber, F. González-Candelas, S. Krautwurst, A. Pérez-Cataluña, W. Randazzo, G. Sánchez, and M. Marz.
- "The structural basis of the genetic code: amino acid recognition by aminoacyl-tRNA synthetases"
F. Kaiser, S. Krautwurst, S. Salentin, V. J. Haupt, C. Leberecht, S. Bittrich, D. Labudde, and M. Schroeder
Scientific Reports, 10, 12647
- "Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases"
F. Kaiser, S. Bittrich, S. Salentin, C. Leberecht, V. J. Haupt, S. Krautwurst, M. Schroeder, and D. Labudde
PLOS Computational Biology, 14(4): e1006101